It was formed in 1936, as a result of the Amalgamation of The Middlesex Light Infantry and The Huron Regiment.

[1][2][3] During the South African War, the 26th Regiment Middlesex Light Infantry contributed volunteers for the Canadian Contingents, most notably for the 2nd (Special Service) Battalion, Royal Canadian Regiment.

[9] On 22 December 1915, the 135th Battalion, CEF was authorized and embarked for Great Britain on 24 August 1916.

[7] On 22 December 1915, the 161st Battalion, CEF was authorized and embarked for Great Britain on 1 November 1916.

[1][2][4][6][10] On 1 September 1936, as a result of the 1936 Canadian Militia Reorganization, The Middlesex Light Infantry was Amalgamated with The Huron Regiment to form The Middlesex and Huron Regiment.