Nutty Professor II: The Klumps is a 2000 American science fiction comedy film directed by Peter Segal and starring Eddie Murphy and Janet Jackson.

Like the first film, the sequel's theme song is "Macho Man" by Village People, which this time is played during the end credits.

Sherman becomes determined to permanently rid himself of Buddy when his antics ruin a dinner in honor of his father Cletus' retirement; and a marriage proposal to Denise.

Despite his assistant, Jason, warning him of the harmful consequences, Sherman uses Denise's methodology to isolate and remove the DNA where Buddy has manifested.

He subsequently visits the pharmaceutical company, making a rival bid of $149 million with Leanne Guilford, President of Acquisitions, for the youth formula.

The traumatized and furious Richmond fires Sherman, who soon learns from Jason that his brain's deterioration has worsened, so he decides to break up with Denise.

Cletus reconciles with Anna and consoles a depressed Sherman, and inadvertently gives him the solution to regaining his intelligence: getting Buddy Love back into his DNA.

Buddy catches the ball in his mouth, and the youth formula transforms him back into a toddler, then further into a glowing mass of sentient genetic material.

During the wedding reception, Sherman's older brother, Ernie Klump Sr., sings a song in honor of the couple, while Richmond continues to be hexed by the now normal-sized hamster.

[5] Nutty Professor II: The Klumps grossed $42.5 million in its opening weekend, beating out Thomas and the Magic Railroad and What Lies Beneath to reach the number one spot.

The site's consensus states that "While Eddie Murphy is still hilarious as the entire Klump family, the movie falls apart because of uneven pacing, a poor script, and skits that rely on being gross rather than funny.

"[12] The New Yorker's Anthony Lane was particularly severe; in addition to hating the film, he dismissed Murphy's playing of multiple characters as "minstrelling," and charged the actor with "at once feeding us what we like and despising us for swallowing it.

Remarked the unnamed critic who reviewed the film for the teletext service: This sequel is disappointing and inferior to the 1996 original, but it still provides exuberant fun.