The Persistence of Chaos is a work of art consisting of a laptop that contains six computer viruses, worms, and pieces of malware that have caused major damage.

Guo O Dong described it as a bestiary for historical malware, and expressed concern about the high price for which it sold, stating that he would either spend the money on another project or burn it.

[3] Guo O Dong originally intended to title the work Antivaxxer in reference to vaccine hesitancy, but changed the name as the intent of the artwork shifted during its creation.

He noted that the amount of public interest in The Persistence of Chaos was thought-provoking for him, stating that "this piece could be considered an exhibit of historical weaponry" and questioning why someone wanted to spend so much money on acquiring it.

Faye Mitchell, the deputy director of Coventry University's School of Computing, Electronics and Mathematics, expressed the concern that the artwork was a distortion and trivialization of cybersecurity and its purpose.