Crumb created the Snoid in his sketchbook in the winter of 1965/1966;[1] the character first appeared in print in the Philadelphia underground newspaper Yarrowstalks #2 (July 1967).

In one story, a "certain mountain" in Tibet is filled with numerous Snoids who sexually assault "Horny Harriet Hotpants"; she later ends up marrying Jesus.

[4] In a story that appeared in Mr. Natural #2, Mr. Snoid has inspired a cult called The Snoidians, who cart him around on the shoulders of the "Giant Daughter of the Snoidvoid".

The Snoidians battle with the "Mr. Naturalists", destroying the Snoid's conveyance and forcing him and Mr. Natural to escape the violence together.

[5] Underground comix writer M. Steven Fox wrote about the Snoid: The ... character is, bottom line, a short-statured asshole, and many people believe that Snoid, with his fetishes, sex cravings and disdain for materialism, is little more than an alter ego for Crumb.