The series serves as a sequel to the My Chemical Romance album Danger Days: The True Lives of the Fabulous Killjoys, focusing on the followers of a group of vigilantes trying to continue their fight against a tyrannical megacorporation in a post-apocalyptic future.

Gerard first announced the project, that would be co-written with Shaun Simon, at the 2009 San Diego Comic-Con[3] and in 2012 New York Comic Con stated that artist Becky Cloonan would be producing the artwork.

[6][7] On September 21, 2020, Gerard Way announced a 6-issue sequel for the series titled The True Lives of the Fabulous Killjoys: National Anthem, which will explore the origins of the members.

On May 7, 2014, two separate collected editions of issues 1 through 6, as well as the Dead Satellites one-shot from Free Comic Book Day 2013, became available online through Things from Another World.

One edition is a standard 160-page trade paperback, while the other, titled The True Lives of the Fabulous Killjoys: California, is a hardcover limited to just 2,500 copies, filled 232 pages and featured an extensive sketchbook with artwork from Becky Cloonan, Gabriel Bá, Paul Pope, Gerard Way, Fábio Moon, Rafael Grampá and Brian Ewing.