However, in his actual school life, Keima is called otamega (オタメガ), a derogatory portmanteau of the two words otaku (オタク) and megane (メガネ, glasses).

At the start of the series, Keima receives an e-mail offering him a contract to "conquer" girls and, thinking it is an invitation to a game challenge, he accepts.

After winning the hearts of fourteen girls (and capturing the spirits residing in them), Keima and Elsie are given an even greater mission: to awaken the six goddesses known as the Jupiter Sisters.

This time however, they remember the encounters he has had with them already, due to the goddesses inside them, causing high tension and constant possible failure as he tries to conquer the girls simultaneously.

Upon arriving, they team up with a mysterious girl who apparently has some connection with Dokuro, Elsie's superior in the underworld, and Keima discovers that several occurrences in the past are different from what he remembers, leading to a tragic chain of events that he must avert to ensure that the present stays unaltered, as well as another demon faction which releases giant humanoid monsters.

[14] Another spin-off series, titled Kami Nomi zo Shiru Sekai On the Train (神のみぞ知るセカイ　ｏｎ　ｔｈｅ　ｔｒａｉｎ), was serialized on the Club Sunday website in 2014.

A second light novel entitled The World God Only Knows 2 Prayer and Curse and Miracle (神のみぞ知るセカイ 2 祈りと呪いとキセキ, Kami nomi zo Shiru Sekai Inori to Noroi to Kiseki) was released on May 18, 2010.

[19] It was announced that script writer Hideyuki Kurata, character designer Watanabe Akio, and director Shigehito Takayanagi would be working on the project.

[25][26] The third season, titled The World God Only Knows: Goddesses (神のみぞ知るセカイ 女神篇, Kami Nomi zo Shiru Sekai: Megami-Hen), aired on TV Tokyo from July 8 to September 23, 2013, and was simulcast on Crunchyroll.

[2] A third OVA, titled Kami Nomi zo Shiru Sekai: Tenri-Hen (神のみぞ知るセカイ　天理篇, "The World God Only Knows: Tenri Arc"), was released in two parts with the 19th and 20th volumes of the manga, on October 16 and December 18, 2012.

Yet the show's sharp sense of humor, honest emotions, and polished production values prove that working with the right prodding and poking, any anime series can indeed become greater than the sum of its parts.