Thioamide

[4] The Willgerodt-Kindler reaction can give benzylthioamides via an analogous process.

A well-known thioamide is thioacetamide, which is used as a source of the sulfide ion.

Using thioacetamide as representative: the C-S, C-N, and C-C distances are 1.68, 1.31, and 1.50 Å, respectively.

Analogues of peptides can also be used as drugs with an improved oral bioavailability.

Maximum effects occur only after a month, since hormone depletion is caused by reduced synthesis, which is a slow process.