It is an analogue of amphetamine where the phenyl ring has been replaced by thiophene.
[1][2] Like amphetamine and most of its analogues, thiopropamine most likely is a norepinephrine–dopamine reuptake inhibitor and/or releasing agent.
[citation needed] Thiopropamine is likely to be metabolized into active 4-hydroxymethiopropamine and thiophene S-oxides.
[3][4] These are further deaminated by CYP2C in liver transforming them into inactive 1-(Thiophen-2-yl)-2-propan-2-one which is a phenylacetone derivative.
[6][7] Derivatives of thiopropamine include the following: This drug article relating to the nervous system is a stub.