[8] During his interview with Genius, Residente mentions that when he went to the United States, as a Latino, he was uncomfortable with the fact that they used the term to refer only to the country.

[8] The lyrics of the song also mention gangs, immigration, murdered journalists, economic depressions, drug trafficking, police brutality, false positive cases in Colombia, "5 presidents in 11 days", people in exile, as well as various other topics.

Sony Music Latin said that it "shares the message the cultures and countries of the American continent are one" and urges "not to separate and create an evolution for unity".

Some scenes show a woman breastfeeding her child through the fence that separates the United States from Mexico; a scene depicting the execution of Túpac Amaru II; scenes countering elements of capitalism (represented in the video as Starbucks and Amazon) with images of indigenous children or pre-Columbian monuments in first world settings; the representation of one of the most emblematic photographs of the strike in Bogotá in 2021,[5] Francisco Martinez, a juggler who used machetes (which some accounts claimed were toys) who was killed by the Carabineros in Chile;[12] the shoe shine cultural revolution in Bolivia; the guerrillas, drug traffickers and favelas; the 43 students who disappeared in Ayotzinapa; as well as the strong offensive by agents in the favelas before the 2014 World Cup in Brazil.

[5][13] Jair Bolsonaro, then president of Brazil, is introduced by a double eating an expensive meal in front of an aboriginal girl and wiping his mouth with the flag of his country.

[4][5] Regarding these images, the musician explained that: “He could have parodied many other political leaders who have been committing atrocities, but Bolsonaro has something particular and if I have to imagine someone wiping their mouth with the flag, it is surely him.

[4] After the lyrics "Gambino my brother, this is America" is heard, a scene is shown, which can be compared to the scene at the beginning of the This Is America music video, but it is mainly depicting the murder of Victor Jara, a Chilean musician who was tortured and later executed by the Chilean military shortly after the 1973 US-supported coup in that country in the Chile Stadium (now Victor Jara Stadium).

An injured girl is later being dragged towards a group of people, also on the ground, surrounded by police, where it is later shown a palenquera woman (with her clothing representing the Colombian flag upside down, as a symbol of the protests in the country) observing the events with indignation.