"[3] Each episode is about an hour in duration and generally starts with a firsthand account of someone affected by the disease.

After that, the hosts create a mixed drink that is connected to the disease, called a 'Quarantini',[4] in a segment known as 'Quarantini time'.

[5] "The Erins," as they've coined themselves, started "This Podcast Will Kill You" because they felt that the medical knowledge that they have gained from their education rarely transfers out of the academia world.

[6] They wanted to make medical knowledge more accessible and easier to understand to the general public, without diluting it.

Season 6 contains a miniseries of bonus episodes which features interviews with authors of popular science books, covering topics ranging from why sweat matters to the history of food safety, from the menstrual cycle to the persistence of race science.