The Kavanaugh and Southgate branches of his family held elected office and positions of leadership in the Methodist church.

As personal physician to Patrick Henry, Hinde played a critical role in the American Revolutionary War through his vaccinations against smallpox and treatment of wounded soldiers.

Shortly after, he was commissioned as a Surgeons' Mate in the Royal Navy and sailed for America with the forces commanded by General Amherst.

He formed a close friendship with an unnamed Virginian who persuaded him to settle in a place called Hobbs Hole in Essex County, Virginia and practice medicine.

[13] In 1765, after he settled in Virginia, Hinde became acquainted with Patrick Henry, one of the founding fathers of the United States, Samuel Davis, and Lord Dunmore.

His association with Henry and settlement in Virginia helped Hinde become acquainted with many of the leading members of society during the period.

When Hinde first met Hubbard, he found her to "possess a great flow of animal spirits, full of humor, gay and lively inner temperament and disposition, with strong powers of mind, and at the same time active and sociable".

[15] According to a biography written by George Coles in 1857, Henry's statesmanlike eloquence and political principles made a strong impression on Hinde and shifted him from being a staunch royalist to a "sturdy republican".

[16] Hinde took an active part in the American Revolutionary War, serving as a surgeon with Patrick and in various campaigns and battles.

His involvement in it was the turning point that led him to embrace the cause of the oppressed colonies against Lord Dunmore and the English royalty.

[17] The Gunpowder Incident was a conflict early in the American Revolutionary War between Lord Dunmore, the Royal Governor of the Colony of Virginia, and militia led by Henry.

Because of insufficient funds in the Continental Army, Hinde was forced to cover the costs of inoculations, which "seriously impaired his private fortune".

The blank was filled with twenty thousand, and placed in the hands of Patrick Henry to select and locate the lands.

Hinde later felt guilt for having banished his daughter and performed medical operations on his wife, and he converted to Methodism.

According to one account: At another time he was taking a morning walk and met Gen. James Taylor, a relative by marriage, who said, 'Good-morning, doctor; where are you going?'

The general, at that time, had some doubts about whether his road led to the same country, and made no reply; but it is hoped he found the way to everlasting life before he left the world.