Thomas Jefferson Strait (December 25, 1846 – April 18, 1924) was a U.S. Representative from South Carolina.

Born in Chester District, South Carolina, Strait attended the common schools of Mayesville, South Carolina, and Cooper Institute, Mississippi.

During the Civil War entered the Confederate States Army in 1862 and served throughout the war, first in Company A, Sixth Regiment of Infantry, and later as sergeant in Company H, Twenty-fourth Regiment, Gist's brigade.

He was graduated from South Carolina Medical College at Charleston in 1885 and practiced medicine.

He resumed the practice of his profession in Lancaster, South Carolina, and died there on April 18, 1924.