[2][3] He attended Thomas Sprigg Wootton High School but dropped out and started taking acting classes while working at a hardware store.

[5][6] He was initially homeless and lived out of his car, often doing street performances to earn money:[7] "I had two songs in my repertoire that I hammered to death, 'Hey Joe' and 'Knockin' on Heaven's Door'.

[4] After arriving in Hollywood, Jane's early roles included Zeph in Buffy the Vampire Slayer (1992), directed by Fran Rubel Kuzui, and the film Nemesis (1992).

He also had supporting roles in several high-profile films, including The Crow: City of Angels (1996), Boogie Nights (1997), The Thin Red Line (1998), Thursday (1998), and Magnolia (1999).

[9] Along with director Jonathan Hensleigh and Avi Arad, Jane has said he was the first and only actor to be asked to play the title role in the film The Punisher (2004).

After finding out that the character was not a traditional superhero, but more of an antihero and a vigilante crime fighter, he accepted,[10] became a fan, then trained for several months with Navy SEALs, gaining more than 25 pounds (11 kg) of muscle.

[12] In addition to his screen work, Jane has appeared several times on stage, and received strong critical reviews as Tom in Tennessee Williams' The Glass Menagerie, and as Chris in Arthur Miller's All My Sons.

[19][20][21] In 2009, Jane starred with Ving Rhames in the crime film Give 'Em Hell, Malone, which premiered at San Diego Comic-Con.

He plays the character of Ray Drecker, a high-school history teacher and basketball coach, who after attending a self-help class while being down on his luck, decides to market the large size of his penis as a path to success.

[29] At the 2012 San Diego Comic-Con, Jane debuted an independently financed Punisher short film, Dirty Laundry, directed by Phil Joanou and co-starring Ron Perlman.

Jane portrays the lead role of Detective Joe Miller in this futuristic saga, in which humans have colonized both Mars and the Asteroid Belt.

[citation needed] After meeting through mutual friends in 2001, Jane and actress Patricia Arquette became engaged in 2002 and had a daughter together before marrying on June 25, 2006, at the Palazzo Contarini del Bovolo in Venice, Italy.