He served as the director of a hospital for the Confederate States Army in Nashville, Tennessee, during the American Civil War.

His father, Reverend Thomas Maddin, was a pastor of the Methodist Episcopal Church, South.

He attended the medical school at the University of Louisville from 1847 to 1849, when he received an M. D.[1] Maddin practiced medicine under Dr. Jonathan McDonald in Limestone County, Alabama.

[1] During the American Civil War of 1861–1865, he was the director of a hospital for personnel of the Confederate States Army.

[1][2] As the medical school re-joined the University of Nashville in 1895, Maddin served as its chair of nervous diseases and general pathology until 1905.