[1] It is entirely paved, with the completion of a 10-mile segment between Golden Stream and Big Falls circa 2008–09.

Ramos Highway provides important access to a number of Mayan ruins and natural areas.

The ancient Mayan sites of Nim Li Punit and Lubaantun are each situated a few miles west of the highway in southern Belize.

The Cockscomb Basin Wildlife Sanctuary is several miles west of the highway in south-central Belize.

[2] In 2011, a project was initiated, and complete by 2015, to extend the Southern Highway 21.4 mi/34.5 km to Jalacte in southwestern Belize.