Thromboxane B2

It is almost completely cleared in the urine.

It itself is not involved in platelet activation and aggregation in case of a wound, but its precursor, thromboxane A2, is.

Thromboxane A2 synthesis is the target of the drug aspirin, which inhibits the COX-1 enzyme (the source of thromboxane A2 in platelets).

[1] 2-(3,4-Di-hydroxyphenyl)-ethanol (DHPE) is a phenolic component of extra-virgin olive oil.

An olive oil fraction containing DHPE can inhibit platelet aggregation and thromboxane B2 formation in vitro.