Tirso González de Santalla (18 January 1624 – 27 October 1705) was a Spanish theologian who was elected, in 1687, the thirteenth Superior General of the Society of Jesus.
Concerned that most Jesuits were in favour of probabilism, the Pope made it clear that González, a rare probabiliorist in the Society, was his candidate.
Pope Innocent XII ordered a new examination of it to be made, and with many corrections it finally appeared in 1694, under the title Fundamentum Theologiae moralis id est, tractatus theologicus de recto usu opinionum probabilium.
González's apologetic Selectarum disputationum tomi quattuor (1680) contains chapters against the Thomists, Jansenists, and some doctors of Louvain; treatises on the Immaculate Conception, and on papal infallibility.
This last, directed against the Declaration of the Clergy of France of 1682, and printed by the order of Innocent XI, was afterwards suppressed by Alexander VIII, who feared new difficulties with the French court.