Due to his father's long reign he came to the throne at a late age since one of his sons, named Ili-bani, was a witness in a contract (and so already a grown man) eleven years before Puzur-Ashur II became ruler.
Although politically astute and a capable soldier, Ishme-Dagan I became embroiled in a struggle for dominance of the Near East with Hammurabi, an Amorite who had turned the hitherto minor town of Babylon into a major city-state and begun a war of conquest, creating the Babylonian Empire.
This perhaps reflects the extent to which Shamshi-Adad and his successors identified with the prestigious Dynasty of Akkad, although the earlier Rimush was apparently assassinated by his own courtiers, “with their seals”, according to a liver-omen of the monumental Bārûtu series, a somewhat ignominious end.
Asinum is believed to had been a descendant of Shamshi-Adad who had founded the brief, foreign Amorite dynasty apparently greatly resented by the native Assyrians judging by an alabaster slab inscription left by Puzur-Sin.
"[19] Middle Assyrian texts recovered at ancient Dūr-Katlimmu, include a letter from Tukulti-Ninurta to his sukkal rabi'u, or 'grand vizier', Ashur-iddin advising him of the approach of his general Shulman-mushabshu escorting the captive Kashtiliash, his wife, and his retinue which incorporated a large number of women,[22] on his way to exile after his defeat.
[23] He stretched the Assyrian Empire further south than before, conquering Dilmun, a pre-Arab civilisation of the Arabian Peninsula that encompassed modern Bahrain, Kuwait,[24][25] Qatar and the coastal regions of the Eastern Province of Saudi Arabia.
Another very brief period of internal upheaval followed the death of Ashur-Dan I when his son and successor Ninurta-tukulti-Ashur (1133 BC) was deposed in his first year of rule by his brother Mutakkil-Nusku and forced to flee to Babylonia.
In his fifth year, Tiglath-Pileser again attacked Commagene, Cilicia and Cappadocia, and placed a record of his victories engraved on copper plates in a fortress he built to secure his Anatolian conquests.
Eriba-Adad II ruled for only two years, and in that time continued to campaign against the Arameans and neo-Hittites before he was deposed by his elderly uncle Shamshi-Adad IV (1053–1050 BC) who appears to have had an uneventful reign.
His successor, Tukulti-Ninurta II (891–884 BC) consolidated Assyria's gains and expanded into the Zagros Mountains in modern Iran, subjugating the newly arrived Persians, Parthians and Medes as well as pushing into central Asia Minor.
Ashurnasirpal II (883–859 BC) was a fierce and ruthless ruler who advanced without opposition through Aram and Canaan (modern Syria, Lebanon, Jordan and Israel) and Asia Minor as far as the Mediterranean and conquered and exacted tribute from Aramea, Phrygia and Phoenicia among others.
Tiglath-Pileser III (745–727 BC), a usurper whose original name was Pulu, initiated a renewed period of Assyrian expansion; Urartu, Persia, Media, Mannea, Babylonia, Arabia, Phoenicia, Israel, Judah, Samaria, Nabatea, Chaldea, Cyprus, Moab, Edom and the Neo-Hittites were subjugated, Tiglath-Pileser III was declared king in Babylon and the Assyrian empire was now stretched from the Caucasus Mountains to Arabia and from the Caspian Sea to Cyprus.
He concentrated on rebuilding Assyria within its natural borders, from Tur Abdin to Arrapha (Kirkuk), he built government offices in all provinces, and created a major economic boost by providing ploughs throughout the land, which yielded record grain production.
Shalmaneser III (858–823 BC) had his authority challenged by a large alliance of a dozen nations, some of which were vassals, including; Babylonia, Egypt, Elam, Persia, Israel, Hamath, Phoenicia, the Arabs, Arameans, Suteans and Neo-Hittites among others, fighting them to a standstill at the Battle of Qarqar.
He then defeated Aramea, Israel, Moab, Edom, Urartu, Phoenicia, the Neo-Hittite states and the desert dwelling Arabs of the Arabian Peninsula, forcing all of these to pay tribute to Assyria.
His armies penetrated to The Caucasus, Lake Van, and the Taurus Mountains; the Hittites around Carchemish were compelled to pay tribute, and the kingdoms of Hamath and Aram Damascus were subdued.
He consolidated Assyrian control over the regions conquered by his predecessors and, by the end of his 27-year reign, Assyria was master of Mesopotamia, The Levant, western Iran, Israel, Jordan and much of Asia Minor.
Shalmaneser V (726–723 BC) consolidated Assyrian power during his short reign, and repressed Egyptian attempts to gain a foothold in the near east, defeating and driving out Pharaoh Shoshenq V from the region.
Tiglath-Pileser III also introduced Mesopotamian Eastern Aramaic as the Lingua Franca of Assyria and its vast empire, whose Akkadian infused descendant dialects still survive among the modern Assyrian Christian people to this day.
The new king firmly subjugated the areas that were previously only under nominal Assyrian vassalage, conquering and deporting troublesome Aramean, Neo-Hittite and Hurrian populations in the north to far-off places.
Adad-nirari II then twice attacked and defeated Shamash-mudammiq of Babylonia, annexing a large area of land north of the Diyala River and the towns of Hīt and Zanqu in mid Mesopotamia.
Mannea, Cilicia Cappadocia and Commagene were conquered, Urartu was ravaged, and Babylonia, Chaldea, Aram, Phoenicia, Israel, Arabia, Cyprus and the famed Midas (king of Phrygia) were forced to pay tribute.
Egypt, now under a Nubian dynasty, once again attempted to gain ground in the region by supporting Israel's rebellion against the empire, however Sargon II once again crushed the uprising, and Piye was routed and driven back over the Sinai.
The Babylonians, Egyptians, Elamites, Cimmerians, Scythians, Persians, Medes, Manneans, Arameans, Chaldeans, Israelites, Phoenicians and Urartians were vanquished and regarded as vassals and Assyria's empire was kept secure.
He imposed a so-called Vassal Treaty upon his Persian, Parthian and Median subjects, forcing Teispes of Persia and Deioces of Media to submit both to himself, and in advance to his chosen successor, Ashurbanipal.
To the west, Aramea (Syria), the Phoenicians, Israel, Judah, Samarra and Cyprus were subjugated, and the Hellenised inhabitants of Caria, Cilicia, Cappadocia and Commagene paid tribute to Assyria.
Shamash-shum-ukin raised a powerful coalition of vassal peoples resentful of being subject to Assyria, including- Babylonians, Chaldeans, Persians, Medes, Arameans, Suteans, Arabs, Elamites, Scythians, Cimmerians, Phoenicians, Israelites and even some disaffected Assyrians.
Ashurbanipal then wrought savage revenge, Elam was utterly destroyed, the Aramean, Chaldean, Sutean tribes were brutally punished, Arabia was sacked and ravaged by the Assyrian army, and its rebellious sheikhs put to death.
Esarhaddon (680–669 BC) expanded Assyria still further, campaigning deep into the Caucasus Mountains in the north, defeating king Rusas II and breaking Urartu completely in the process.
Sin-shumu-lishir was defeated after three months of civil war, but remaining tensions led to wholescale revolution in Babylonia, and during the reign of Sin-shar-ishkun many Assyrian colonies to the west, east and north similarly took advantage and ceased to pay tribute to Assyria, most significantly the Medes, Persians, Scythians, Cimmerians, Babylonians, Chaldeans and Arameans.