Triiodothyroacetic acid is also a physiologic thyroid hormone that is present in the normal organism in low concentrations.

Tiratricol is an analogue of a naturally circulating metabolite of the active thyroid hormone T3.

[1] Once inside cells, tiratricol activates the thyroid hormone receptor in a similar way to endogenous T3.

It was once an approved medication in Brazil, but its marketing authorization was suspended in 2003, effectively prohibiting its sale.

In 1999 and 2000, the United States Food and Drug Administration and Health Canada both issued warnings to the public regarding the use of dietary supplements containing tiratricol.