Tissue tropism

[1] For example, rabies virus affects primarily neuronal tissue.

Similarly, JC virus (JCV) primarily affects and resides in kidneys.

[3] Factors influencing viral tissue tropism include: The cellular receptors are the proteins found on a cell or viral surface.

The way that these proteins are acquired is through a similar process to that of an infection cycle.

Tissue tropism develops in the following stages: Example: HIV has a gp120, which is precisely what the CD4 marker is on the surface of the macrophages and T cells.