Tithoes confinis, common name giant longhorn beetle, is a species of beetle of the family Cerambycidae.

Tithoes confinis can reach a length of 55–100 millimetres (2.2–3.9 in).

This beetle has a massive hairy body and strong mandibles.

Larvae feed on cashew nut trees (Anacardium occidentale) and other trees of the family Anacardiaceae.

This widespread species can be found in forests through most of the continental Afrotropics (Djibouti, Ethiopia, Kenya, Malawi, Mozambique, Somalia, South Africa, Tanzania, Uganda, Zambia and Zimbabwe).