Titus Atilius Rufus (died AD 85) was a Roman senator, who held several appointments during the reigns of Nero, Vespasian and Domitian.

The first province he is known to have administered was a public one, Creta et Cyrenaica;[2] Werner Eck dated this governorship to the year 67.

[4] Immediately afterwards Rufus was appointed to the imperial province of Syria, where Eck dates his governorship from 82 to 85.

[5] According to Tacitus, Rufus died while governor of Syria; Tacitus' father-in-law Gnaeus Julius Agricola was mentioned as a possible successor to Atilius Rufus, but Domitian never offered it to Agricola.

[6] Titus Atilius Rufus Titianus, the consul of 127, may be his son.