[12] On March 9, 2018, What So Not released the album Not All the Beautiful Things, which contained the song "Monsters" featuring Adeyemi and Michael Christmas.

[citation needed] On April 27, 2018, he released the tobi lou and the Loop EP, which contained the song "Buff Baby", which gained significant traction on TikTok.

On August 2, 2019, he released his debut full-length studio album, Live On Ice, featuring guest appearances from Erica René, Cam O'bi, Rockie Fresh, Soundbwoy, okay(K),[20] Glassface, Vernon, Ryan Destiny, Djemba Djemba, and LeJKeys.

[16] On March 11, 2022, his studio album Non-Perishable was released, featuring guest appearances from T-Pain, Jean Deaux, and Chika.

[16] On April 2, 2021, Rockie Fresh released the album Slid Thru Pt 2, featuring Adeyemi and Jeff Kaale on the song "Gucci".

[16] On July 29, 2022, Warren Hue's album Boy of the Year released, featuring Adeyemi on the song "In My Bag.

"[28] On March 31, 2023, he released the album Baggy Weather, featuring guest appearances from Chief Keef and eaJ, as an exclusive on his TobiLoop app.

[32] On June 30, 2023, he released the album 'Decent, featuring guest appearances from Dame D.O.L.L.A., Polo G, rä lomac, Glassface, Chief Keef, Saba, and internetboy.

[35] Tobi Lou has stated that artists including André 3000, The Notorious B.I.G., Will Smith, Tupac, NSYNC, Timbaland, Frank Ocean, Missy Elliott, Maroon 5, Pharrell Williams, and Kanye West are inspirations for him.