Tokugawa Mitsutomo (徳川 光友, August 31, 1625 – November 26, 1700) was daimyō of Owari Domain during early Edo period Japan.

As a further sign of favor, his official wife, Chiyohime later Reisen-in, was also the daughter of shōgun Tokugawa Iemitsu.

He completed the clan mortuary temple of Kenchu-ji the following year, and was raised to upper 3rd court rank and Chūnagon on August 12, 1653.

During this period, he lived at the Ōzone Oshitayashiki, a palatial palace with extensive gardens some distance from Nagoya Castle.

He proved so adept that he was named the 6th sōke by Yagyū Toshikane, and added a number of teaching concepts to the ryū.