Galásek started his career with Banik Ostrava in 1991, before moving to Willem II Tilburg in 1997.

With Willem II, he reached an historic fifth place in Eredivisie, which meant UEFA Cup qualification for the first time in 30 years.

In July 2009, he retired from professional football[3][4] but made a comeback in the Bayernliga on 31 August 2009 when he signed for FSV Erlangen-Bruck.

Galásek made his debut for the Czech Republic in 1995 and was part of the team that reached the semifinals of Euro 2004.

In June 2008, after a loss to Turkey at UEFA Euro 2008, he left the national team and ended his international career.

In the season of 2011–12, Galásek trained the U15 team in FSV Erlangen-Bruck, where his son played.