[3] In April 2018, it was announced that Golisano was purchasing Greenlight Networks, a Rochester-based fiber internet provider and local competitor to Frontier Communications and Charter Spectrum that was established in 2012.

[5] However in 2022, Golisano sold his controlling equity shares of Greenlight Networks to the investment firm Oak Hill.

[6] The 2020 Forbes 400 list stated that Golisano was the 238th wealthiest person in America with a net worth of $3.4 billion as of September 2020.

[12] Golisano made a bid for the bankrupt Los Angeles Dodgers franchise in early 2012,[13] but his group was eventually outbid by a consortium led by Magic Johnson and the Guggenheim Partners.

[16] By receiving more than 50,000 votes each time, Golisano brought the Independence Party an automatic ballot line for the succeeding four years.

[18] In July 2008, Golisano formed a PAC called Responsible New York and funded it with $5 million of his own money.

Golisano vowed to fight Mayor Michael Bloomberg's proposal to extend term limits, arguing that the people of New York City have voted twice in favor of the current law.

[19] There was speculation that he would run for governor again on the Republican ticket, but it was announced, on May 15, 2009, that he was moving to Florida to escape New York's high taxes.

[20] In June 2009, Golisano took partial credit for creating the 2009 New York State Senate leadership crisis in which Republicans temporarily seized control of a body that still retained a Democratic enrollment edge.

He orchestrated the defection of Democratic senators Pedro Espada Jr. and Hiram Monserrate, who voted with Republicans to reinstate Dean Skelos as majority leader.

The center, which provides integrated health care to people with disabilities and their families, was made possible with a gift of $3.5 million from Golisano.

[34] In September 2016, Golisano gave $7.5 million to Nazareth University for a new athletic training center that will aim to be a model of inclusion, fitness and wellness, and is expected to open in 2018.

[36] In April 2017, the City of Rochester announced modified Rochester Broadway Theatre League proposal for Midtown Plaza which in partnership with Morgan Development would include a performing arts center to be called the Golisano Center for the Performing Arts in honor of a donation made to the project by Golisano.

[47] Golisano hired Ian Mortimer, who was previously the associate provost at the Rochester Institute of Technology, as the school's first president.

[47] In February 2020, Golisano released Built, Not Born: A Self-Made Billionaire's No-Nonsense Guide for Entrepreneurs, co-authored by Mike Wicks.