Tomasz Antoni Zamoyski (1707–1752) was a Polish nobleman (szlachcic) who served as the voivode (governor) of Lublin Voivodeship.

In 1733, he supported the election of Stanisław Leszczyński to the Polish throne.

In 1744, he was appointed the voivode (governor) of Lublin Voivodeship.

He was awarded the Knight of the Order of the White Eagle on 3 August 1746.

He was married to Marianna Lubienska and Aniela Teresa Michowska.