[1] Due to the rapid spread of TYLCV in the last few decades, there is an increased focus in research trying to understand and control this damaging pathogen.

C2, C3, and C4 proteins have been associated to function as a post-transcriptional gene silencing suppressor, a virus accumulation enhancer, and a symptom induction determinant, respectively.

[1] In the insect vector, a study found that TYLCV had a high binding affinity to a GroEL homolog, a molecular chaperon essential for protein folding.

Treatments that are commonly used for this disease include insecticides, hybrid seeds, and growing tomatoes under greenhouse conditions.

Developing countries are most affected by this crop disease due to both the climate and the high costs of treatments used in order to control it.

[1] TYLCV is found in tropical and subtropical regions, and it is one of the most important pathogens against tomato crops around the world.

The first detection of TYLCV was confirmed through blot hybridization, PCR, and genome sequencing in the Dominican Republic in 1994.

Bemisia tabaci has a wide geographical distribution, and it can be found in Asia, Africa, North, Central, and South America, and Australia.

Currently, the most effective treatments used to control the spread of TYLCV are insecticides and resistant crop varieties.