In Japan, the police investigate the murder of high school girl Tomie Kawakami (Miho Kanno).

The detective (Tomoro Taguchi) assigned to the case learns that three years prior another Tomie Kawakami was murdered in rural Gifu prefecture.

The detective tracks down one of Tomie's classmates called Tsukiko Izumisawa (Mami Nakamura), an art student who is being treated for amnesia.

Over the span of a couple weeks, it grows into a beautiful teenaged girl with orange eyes responding to the name of Tomie Kawakami.

Tomie starts emotionally taunting Tsukiko, taking unflattering selfies and pictures with and of her, and attempting to feed her live cockroaches.

Director Ataru Oikawa admired the original manga for Tomie, referring to it as a "fairy tale in bad taste".

[3] Oikawa's script draws characters and situations from the stories "Photograph" and Kiss" in Ito's original manga, although not "Mansion," which also features Tsukiko as the protagonist.