The Tomifobia River is a flowing body of fresh water in Memphremagog Regional County Municipality, in the Eastern Townships, in the province of Quebec, in Canada.

This has helped protect the river from heavy waterfront housing growth (except near Lake Massawippi in Ayer's Cliff), characteristic of a number of other bodies of water in the area.

[3] While a study by Roberge & Roy (2004) suggests there is little continuously suspended sediment in the river, there are some concerns about the expansion of the Tomifobia delta at the mouth of Lake Massawippi.

A number of rare animal species, including the endangered wood turtle (Clemmys insculpta), have been documented within the wetlands of the Tomifobia valley,[4] the Appalachian Corridor Appalachien (ACA).

Although its meaning is unknown, the origin of the word "Tomifobia" is likely Algonquian, the language spoken by the Abenaki tribes that seasonally travelled on the lake and river systems of the Eastern Townships prior to European settlement.

Today the Tomifobia River is an important tourist attraction, offering recreational summer activities including canoeing/kayaking, cycling, hiking, bird watching, and sport fishing.