Focus areas include hard-to-abate sectors such as heavy industry (steel and iron, chemicals, cement), long-haul transportation (aviation, shipping, trucking) and clean fuels (bio-diesel and ultra-low-sulfur diesel (ULSD).

Topsoe is actively involved in the field of heterogeneous catalysis, contributing significantly to the global production of ammonia for fertilizer The headquarters and main research labs are located in Lyngby, a northern suburb of Copenhagen, Denmark, manufacturing of catalysts is carried out in Frederikssund, Denmark and Bayport Industrial District in the United States.

The company has offices in Argentina, Australia, Bahrain, Brazil, Canada, China, India, Indonesia, Iran, Malaysia, Mexico, Saudi Arabia and the United States.

During World War II, the company got permission to use the labs at the Polytechnic Educational Establishment, and in 1943 they moved to facilities in Hellerup, north of Copenhagen.

[13] In June 2017, Umicore announced "that it has reached an agreement to acquire the heavy duty diesel and stationary catalyst businesses of Haldor Topsoe for an enterprise value of DKK 900 million (approx.

[15] In 2022, Topsoes investment in a factory producing Sustainable Aviation Fuel from palm oil in Manaus, Brazil, was criticized in Danish media.

Experts argue that palm oil is one of the most environmentally damaging biofuels, contributing to deforestation and climate change.

The planned facility, set to produce half a million tons of fuel annually by 2025, raises concerns about biodiversity loss and carbon emissions from deforestation.

Despite Topsoe's claims that the project will adhere to sustainability certifications, critics say the reliance on palm oil undermines genuine climate action and risks worsening environmental degradation in the Amazon.