During his professional career, Francis has played with the Italian League clubs Orlandina Basket and Cantù.

He has also played with the Greek League clubs AEL 1964, AEK Athens, and Panellinios Basket.

[5] In the summer of 2017, Francis, for the fourth year in a row, competed in The Basketball Tournament on ESPN for D.C. on Point.

Competing for the $2 million grand prize, Ramón scored 15 points and grabbed nine rebounds in 30 minutes of play as D.C. on Point fell 80–75 to Team FOE, a Philadelphia based team coached by NBA forwards Markieff and Marcus Morris.

Prior to 2017, Francis competed for Southern Hospitality in 2016 and for the Notre Dame Fighting Alumni in 2014 and 2015.