Giardia lamblia, leishmania, trichomonas vaginalis, and fungi serve as natural hosts.

The virion consists of a single capsid protein and is about 40 nanometers in diameter.

[1] The genome is composed of a monopartite, linear double-stranded RNA molecule of 4.6–6.7 kilobases.

It contains two overlapping open reading frames (ORF) – gag and pol – which respectively encode the capsid protein and the RNA-dependent RNA polymerase.

The virus exits the host cell by cell-to-cell movement.