Toulouse-Matabiau is the main railway station in Toulouse, southern France.

Toulouse waited until the middle of the 19th century for the railway to arrive in the city.

[citation needed] In 1853, Émile Pereire and his brother Jacob founded the CF du Midi.

Three years later, the line from Bordeaux to Toulouse was opened, it was extended to Sète in 1857.

Toulouse-Matabiau is situated at the heart of a six-branch star network of lines with both regional (TER) and national (TGV and Corail) services.