Trabecular bone score

In addition, clinical risk factors for fracture are at best an indirect assessment of the bone quality.

[citation needed] The trabecular bone score is a textural parameter that can be applied to DEXA, which quantifies the local variations in gray level.

[citation needed] It was found that TBS is a reflection of the structural condition of the bone microarchitecture.

Conversely, a low TBS value means that the microarchitecture of bone is incomplete and poorly connected with wide spaces between trabeculae.

[9] As TBS relies on measurement of soft tissue, it is considered unreliable in individuals with a BMI over 37,[10] or with extremely high waist circumference.

Microarchitecture of bone in health and in osteoporosis.
Relative Risk of TBS expressed by standard deviation and compared with relative risks of major clinical risk factors for fracture