A transaxle is a single mechanical device which combines the functions of an automobile's transmission, axle, and differential into one integrated assembly.
Transaxles are nearly universal in all automobile configurations that have the engine placed at the same end of the car as the driven wheels: the front-engine/front-wheel-drive; rear-engine/rear-wheel-drive; and mid-engine/rear-wheel-drive arrangements.
Since this placement of the gearbox is unsuitable for a live axle (due to excessive unsprung mass), the rear suspension is either independent, or uses a de Dion tube (notably in Alfa Romeos).
Over the years, models adopting this configuration have included: All Audi cars with longitudinal engines and their 'trademark' quattro four-wheel-drive (4WD) system, along with their related marques from the Volkswagen Group which share the same layout, utilise a transaxle.
The Nissan GT-R and Ferrari FF (and its successors) are unusual in being all-wheel-drive cars with front-engined layouts and rear-mounted transaxles.