The film stars Johnny Simmons, Gabriel Luna, and Clifton Collins Jr. as border patrol agents who encounter a Mexican drug cartel.

[2] Three agents (Benjamin Davis, Lance Flores, and Lou Hobbs) find some drug evidence in a car at a desert checkpoint, which reveals an insidious plot in their organisation.

Transpecos received its world premiere at South by Southwest in Austin, Texas on March 13, 2016.

John DeFore of The Hollywood Reporter wrote: "Artfully made but wholly accessible for a mainstream audience, it features strong performances but no names in the cast who'll draw attention on their own."

"[6] Kahron Spearman of The Austin Chronicle wrote: "With nail-biting precision, Kwedar has crafted Transpecos into a diamond.