At the Netflix Anime Festival in October 2020, it was revealed that Trese komik artist Kajo Baldisimo and writer Budjette Tan will serve as showrunners.

Yuson forwarded the comic to her fellow producer Shanty Harmayn who convinced her that they should pitch the adaptation of Trese into an animated series.

In May 2018 Netflix reach out to Jay Oliva, who was based in the United States at the time, to work with a potential Trese animated series.

Paul Yap, Ean Mayor and Carlos Tanada did the first demo recording at the Wonder Collab Studios after which it was sent to Armi Millare for finalization.

Other countries where the show ranked were Austria, Bangladesh, Bulgaria, Canada, Estonia, Germany, Kuwait, Lithuania, New Zealand, Nigeria, Oman, Serbia, Singapore, Sri Lanka, and the United States.

He praised the plot, dialogue, animation, and voice acting, calling it "a paranormal Filipino film noir that is both stylish and gripping.

"[36] In the online anthropology magazine SAPIENS, Andrea Malaya M. Ragragio and Myfel D. Paluga noted that the show's portrayal of Talagbusao as "a bloodthirsty, male “god of war” whose nature is to wreak havoc and thrive in it" drew largely from American colonial era anthropologist Fay-Cooper Cole's description of him as a “patron of the warriors and of people who run amuck,” which dates back to the early 1900s.

As a result, they say that " the Talagbusao depicted in Trese barely resembled what Indigenous communities in Mindanao mean when they talk about this entity or its related forms, called busaw."

But Ragragio and Paluga also acknowledged that the show likely changed his characterization "simply to tell an enjoyable detective story, with a Filipino folkloric flair.