TMS is the only anesthetic licensed in the United States for fin fish that are intended for human consumption.

The drug can have selective toxicity for poikilotherms due to their lower rate of metabolism in the liver.

[1] Tricaine is an anaesthetic that operates by preventing sodium ions to enter the cell and thus silencing action potentials.

MSD Animal Health is one of the largest manufacturers of Tricaine in Norway and other European markets under the brand name Finquel.

Fish treated with Tricaine cannot be slaughtered for human consumption until a certain withdrawal period is reached, for example 21 days in the United States for Syncaine.