Built between 1818 and 1839, the building served in several roles throughout the history of Imperial Russia, the Soviet Union, and Russian Federation.

Notable among the patrons of the construction project was the Ryazanovs, a family of merchants and miners based in Yekaterinburg.

At the time of its completion, the church's towers were among the tallest structures in Yekaterinburg and have been cited as an example of early high-rise development in the city.

[1] Following the Russian Revolution and the subsequent formation of the Soviet Union, the church began to be negatively affected by the new government's Atheistic policies, which included the closure of many religious institutions.

The former church would go on to host a cinema and a coat factory during the Soviet era, with many parts of the building sustaining damage.