Tripe palms, also known as acanthosis palmaris, is a medical sign characterized by thick ridged velvety palms, typically as part of a paraneoplastic syndrome.
[1][2] In some, both tripe palms and AN appear together before the cancer is diagnosed.
[1] The sign has also been associated with bullous pemphigoid, psoriasis, and exfoliative dermatitis.
[2] Other conditions that may appear similar include acromegaly, acrokeratosis paraneoplastica, hypertrophic osteoarthropathy, idiopathic hypertrophic osteoarthropathy, palmoplantar keratoderma, and acropachy.
[2] Tripe palms may improve with treatment of the underlying cancer.