[3][5] Historically, the territory of modern-day Tsaghkadzor was a part of the Varazhnunik canton of the Ayrarat province of Ancient Armenia.

Tsaghkadzor was first mentioned as Tsaghkunyats Dzor during the 3rd century when it was formed as a small settlement and quickly became the favourite hunting ground for the Arsacid kings of Armenia.

During the 4th and 5th centuries, Tsaghkunyats Dzor, along the surrounding lands and forests, was placed under the governance of the Varazhnuni noble family by the Arsacid kings.

Starting from the 10th century, the houses of Kamsarakan and Pahlavuni—both related to the Arsacid dynasty by origins—were merged and governed the cantons of Aragatsotn, Kotayk and Varazhnunik.

However, with the establishment of the Zakarid Principality of Armenia in 1201 under the Georgian protectorate, Kecharuyk witnessed a significant rise in economic and cultural life under the rule of the Khaghbakyan and later the Proshyan noble families, during the 13th and the 14th centuries.

After the fall of the Ilkhanate in the mid-14th century, the Zakarid princes ruled over Lori, Shirak, Kotayk, and Ararat plain until 1360 when they fell to the invading Turkic tribes.

[7] On 8 October 1827, a powerful earthquake occurred near Tsaghkadzor, destroying churches in the settlement and affecting communities across northeastern Armenia.

[8] Tsaghkadzor remained under the Persian rule until 1827–28, when Eastern Armenia was ceded by the Russian Empire as a result of the Russo-Persian War of 1826–28 and the signing of the Treaty of Turkmenchay.

[3] With the fall of the Russian Empire and after the decisive Armenian victory over the Turks in the battles of Sardarabad, Abaran, and Gharakilisa, the entire region of Kotayk became part of the independent Armenia in May 1918.

During the Soviet era, Tsaghkadzor was developed as a major resort town, intended to attract a large number of tourists.

Many monumental buildings and dachas previously built by the wealthy merchants of Yerevan and Tiflis were either nationalized or sold in auctions.

With the foundation of many luxurious hotels and sanatoriums, the town became a major winter resort attracting a large number of ski and snowboard enthusiasts from all over the world, to become one of the most developed tourist destinations in Armenia.

On 11 August 2008, around 90 American Peace Corps volunteers, trainees and staff members were relocated[9] to Tsaghkadzor from the Republic of Georgia as a precaution during the military conflict with Russia.

[3] Surrounded with alpine meadows, the town is situated on the southeastern slope of Mount Teghenis, at a height of 1841 meters above sea level.

[11] The Kecharis Monastery is one of the significant religious complexes of Eastern Armenia and a well-preserved example of medieval Armenian architecture.

Tsaghkadzor is one of the three towns of Armenia that are allowed to accommodate gambling houses and activities within the city limits (along with Jermuk and Sevan).

[citation needed] With the diminished number of the town's population, currently Tsaghkadzor is home to 1 public education school.

Entirely renovated and reopened in 2008, it is considered one of the most developed training facilities in the South Caucasus, with its modernized hotel and sanatorium.