It is located at a road distance of 123 km (76 mi) south of the capital Yerevan, on the shores of Srkghonk River (Armenian: Սրկղոնք), at a height of 1,194 meters (3,917 ft) above sea level.

However, the excavated layer of a cemetery and the remains of a mausoleum from the 1st millennium BC testify that the area has been settled long before the 5th century.

According to historical records from the 1st quarter of the 9th century, when Syunats Prince Philip, son of Vasak, moved his residence from Sisian to Vayots Dzor and fortified in Yeghegis, the name Yeghegnadzor or Yeghegyats Dzor spread across the entire province.

Many significant churches, monastic complexes, bridges and caravanserais were built in the region between the 10th and 13th centuries, when Yeghegnadzor was part of the Kingdom of Syunik under the rule of the Siunia dynasty.

The region was turned into a frequent battlefield between the invading troops of the Turkic and Iranian tribes.

In 1828-30, many Armenian families from the Iranian towns of Salmas and Khoy were resettled in Eastern Armenia, particularly in the areas that later became part of the Erivan Governorate in 1840.

In 1870, Yeghegnadzor became part of the newly-formed Sharur-Daralagezsky Uyezd of the Erivan Governorate within the Russian Empire.

Following the independence of Armenia in 1991, Yeghegnadzor became the capital of the newly-formed Vayots Dzor Province as per the 1995 administrative reforms.

The park is also home to a vishapakar (dragon stone) dating back to the 2nd millennium BC.

However, the most popular celebration in the town is the harvest festival, taking place every year on the second Sunday of October.

Locals from all villages take part in the parade on cars decorated with flowers, bringing their own crops, berries typical to their territories.

Yeghegnadzor cheese is made from pasteurized cow's or goat's milk (or both) and mixed with local greens.

It is stored in individual clay pots, then buried in the mountains and left to mature for at least 6 months before consumption.

Light productions of building materials, textile, hand-made carpet and jewellery are also found in the town.

The Royal Victorian University Educational Foundation of Armenia (RVU) is based in Yeghegnadzor.