Tsalka (Georgian: წალკის მუნიციპალიტეტი, Ćalḱis Municiṕaliťeťi; Greek: Δήμος Τσάλκας; Armenian: Ծալկայի Շրջան, romanized: Tsalkayi Šrǰan) is a municipality in Georgia's southern region of Kvemo Kartli, covering an area of 1,050.6 km2 (406 sq mi).

The area of the municipality corresponds to the historical region of Trialeti.

Tsalka municipality is administratively divided into 30 communities (თემი, temi) with 40 villages (სოფელი, sopeli), three urban-type settlements (დაბა, daba) and one city (ქალაკი, kalaki).

The ethnic composition is 46.7% Georgian, 38.8% Armenian, 7.0% Azerbaijani and 6.9% Greek.

Ilia Sabadze of Georgian Dream was reelected as mayor.