He ran a successful business in the 1940s exporting muti products to South Africa.
In 1945, he began a career in the Batwana tribal administration.
[1] In 1965, Tsheko was elected to the 1st Parliament of Botswana to represent the Okavango constituency.
His election was one of only two competitive races in the 1965 Bechuanaland general election, defeating Botswana Independence Party candidate Motsamai Mpho with 53.7% of the vote.
Tsheko died at the end of his term in 1969.