Tuinal was the brand name of a discontinued combination drug composed of two barbiturate sodium salts (secobarbital and amobarbital) in equal proportions.

[3] Eli Lilly has discontinued the manufacture of Tuinal in the United States due to the diminishing use of barbiturates (largely replaced by the benzodiazepine family of drugs) in outpatient treatment, and its widespread abuse.

The pill was known colloquially under the street names "tuies", "tumies", "double trouble", "blue tips", " F-66's" (which were the markings on Lilly's capsule), "rainbows", "beans", "nawls" and "jeebs".

Like other barbiturate depressants, Tuinal promotes physical and psychological dependency beginning after one week of regular use and carries a high risk of overdose.

Tuinal is classified as a Schedule II drug under the Controlled Substances Act in the United States, meaning it requires a prescription from a licensed practitioner.