While in the Southeast and soon after removal, most Muscogee Creek were opposed to all European-American missionaries and their schools, as they did not want their traditional culture disrupted by Christianity.
But in 1842 the Creek Council had authorized Loughridge to set up a mission in Coweta, in order to get the associated school to educate their children.
After assessing this school, the Creek Council allowed Loughridge in 1850 to establish another mission, Tullahassee, northwest of the community of Muskogee.
Loughridge chose the site for Tullahassee Mission and purchased 70 acres (280,000 m2) of land from Thomas Marshall to support the complex.
[2][5] Opened in 1850, it was operated as an Indian boarding school for the next three decades to train both "full- blood" and "mixed-blood" Muscogee students.
In 1906, to extinguish tribal land claims and organization in preparation for Oklahoma to be admitted as a state, the federal government dissolved Creek institutions, including its school system.
In 1908 the US government took over ownership of the site via the United States Department of Interior, which by then had been authorized by Congress to have responsibility for Indian trust lands and treaties.
[7] In 1916, the African Methodist Episcopal Church (the first independent black denomination in the United States, established in Philadelphia, Pennsylvania) founded Flipper-Key-Davis College in Tullahassee.
In the 21st century, the small community of Tullahassee is considered the oldest of the surviving thirteen all-black towns in former Indian Territory.