Turkish Airlines Flight 452 was a scheduled domestic passenger flight operated by a Boeing 727-2F2 of Turkish Airlines that crashed near Isparta on 19 September 1976 while en route from Istanbul Atatürk Airport (IST/LTBA) to Antalya Airport (AYT/LTAI), killing all 154 occupants on board.

The four cabin crew members were Feyzan Güngör, Neriman Düzelli, Kâmuran Küçükkoşum and Canan Dinç.

Three Turkish Airlines employees, scheduled to fly a McDonnell Douglas DC-9 from Antalya to Istanbul the next morning, were also deadheading on the flight.

Captain Topçuoğlu, who was in the passenger cabin, returned to the cockpit after realizing that something was wrong at an altitude of 150 metres (490 ft) and gave full throttle when he saw the hill ahead.

[10] At the time of the accident, a horror film was being aired on television, causing some locals to leave their homes after the explosion.

To prevent the looting of items, officials closed the area to civilians, despite which thousands of people went up the hill and were able to see the wreckage and bodies after midnight.

[11][13] The crash also claimed the life of the former Italian soldier and recipient of the Gold Medal of Military Valour, Enrico Martini.

İlhan Cavcav was on board the aircraft on the first leg and was also due to continue with the flight to Antalya but changed his mind and flew to Ankara instead.

[15] The day following the crash, a lightning strike was eliminated as a cause for the accident, based on the weather reports.

[16] The experts inspecting the recordings later announced that the pilots were trying to fly visually, instead of instrumental flight, which was required at night, and that they mistook the dark area ahead of them—the Western Taurus Mountains—for the Mediterranean Sea[17] and the city lights of Isparta for those of Antalya.

[7] It was also revealed that the distance measuring equipment of Antalya Airport broke three days before the crash.