Two Wells Fargo Center is a 433-foot (132 m) high rise in Charlotte, North Carolina.

[3] The building was designed by LaBella Associates, formerly known as Pease Engineering and Architecture, with David Julian Moore was the architect on-site functioning as construction administrator.

[9] Over the years there have been a few other tenants including Speedway Motorsports leased 20,000 square feet (1,858 m2) in 1998 to house 20 employees,[10] also in 1998 Ruddick Corp., the former owner of Harris Teeter leased space,[11] in 2006 law firm Downer, Walters & Mitchener vacated 6,000 square feet (557 m2) on the 17th floor to move to an office on Morehead St,[12] and CIT Group leased space in the building until 2010.

The employees from these two buildings will be consolidated into 550 South Tryon and Three Wells Fargo Center.

The sale of the property is part of a larger effort by Wells Fargo to reduce its real estate footprint in Uptown.

[18] As of August 2023 CBRE is currently in the early of stages of finding potential buyers to convert the buildings to multifamily residential.

[19] In January 2024 two proposals were submitted to Charlotte Center Partners sponsored Reimagining Vintage Office Design Competition showcased how the building could be redesigned.

The second proposal by Little Diversified Architectural Consulting would convert the entire building into a residential tower and include ground floor retail.

Chris Scorsone the lead designer of the renovation with Little Diversified Architectural Consulting said this about it "We looked at this as just another evolution of the building.

[26] In May 2006, it was repainted from beige to gray to complement the renovated color scheme at the neighboring Wachovia Main.

Before cancelling the project the bank was considering New York architecture firm Kohn Pedersen Fox as one of the two finalists for designing the building.

The other finalist was Atlanta architecture firm Thompson Ventulett Stainback & Associates, which designed One Wells Fargo Center.

[30] However, the plans for the new tower were putting on hold indefinitely in September 1999 due to the company's poor performance on the stock market.