Tzihuacxochitzin I was a Queen consort of Azcapotzalco as a wife of the king Tezozomoc, who was very famous.
She was a daughter of the noble dignitary called Huitzilaztatzin.
She married Tezozomoc, and it is mentioned by Chimalpahin that they had ten children: Xaltemoctzin had a daughter called Tzihuacxochitzin, named after his mother.
Tzihuacxochitzin was a grandmother of Tecollotzin, Tlacateotl, Matlalatzin and Huacaltzintli.
It is possible that she was a mother of the queen Ayauhcihuatl, who was a mother of Aztec emperor Chimalpopoca.